KEGG   REACTION: R04509
Entry
R04509                      Reaction                               
Name
ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase
Definition
ATP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine <=> ADP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate
Equation
Reaction class
RC00002  C00002_C00008  C04556_C04752
Enzyme
Pathway
rn00730  Thiamine metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00127  Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
M00895  Thiamine biosynthesis, prokaryotes, AIR (+ DXP/glycine) => TMP/TPP
M00896  Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP
M00897  Thiamine biosynthesis, plants, AIR (+ NAD+) => TMP/thiamine/TPP
M00898  Thiamine biosynthesis, pyridoxal-5P => TMP/thiamine/TPP
M00899  Thiamine salvage pathway, HMP/HET => TMP
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7
     R04509  ATP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine <=> ADP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate
Orthology
K00877  hydroxymethylpyrimidine/phosphomethylpyrimidine kinase / thiaminase [EC:2.7.1.49 2.7.4.7 3.5.99.2]
K00941  hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
K14153  hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
K21219  hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
Other DBs
RHEA: 19896

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